Prepare the Dough: In a large mixing bowl, combine the warm water, sugar, and yeast. Let it sit for 5–10 minutes until it becomes frothy. This means the yeast is active and ready to give your calzones the perfect rise.
Mix and Knead: Add flour, salt, and olive oil to the yeast mixture. Stir until it forms a dough. Transfer to a lightly floured surface and knead for about 5–7 minutes until smooth and elastic. If using a stand mixer, knead with the dough hook for 4–5 minutes.
Let Dough Rise: Place the dough in a greased bowl, cover it with a clean kitchen towel, and let it rise in a warm spot for 1 hour, or until it doubles in size.
Prepare the Filling: While the dough rises, mix mozzarella, ricotta, ham, pepperoni, Italian sausage, garlic powder, oregano, red pepper flakes (if using), and chopped basil in a medium bowl. Taste and adjust seasoning as needed.
Preheat Oven: Preheat your oven to 425°F (220°C) and line a baking sheet with parchment paper.
Roll Out the Dough: Punch down the dough to release air bubbles. Divide it into 4 equal portions. Roll each portion into a circle about 8 inches in diameter.
Fill the Calzones: Spoon a generous amount of filling onto one half of each dough circle, leaving a 1-inch border around the edges. Add a spoonful of marinara sauce if desired.
Seal the Calzones: Fold the dough over the filling to form a half-moon shape. Press edges firmly and crimp with a fork to seal completely.
Apply Egg Wash: Brush the top of each calzone with beaten egg for a golden, glossy finish. Sprinkle grated Parmesan if desired.
Bake to Perfection: Place calzones on the prepared baking sheet. Bake for 18–20 minutes, or until golden brown and crisp.
Cool and Serve: Let the calzones cool for 5 minutes on a wire rack. Serve warm with marinara sauce on the side for dipping.